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Please read the summary, then complete the reading assignment and prepare a discussion post:
Summary: Women have different physiological make up contributing to differences in the effects of pharmacological agents. This lesson will assist you in understanding some of the differences between men and women. Some aspects of the reading will get into rather detailed and cellular aspects. Students are not expected to understand these details. However, when the readings discuss specific enzymes, for example, rather than knowing each of the enzymes, simply recognize the broader picture that different enzymes are involved in the pharmacokinetics.
The goal is to understand broadly, the physiological differences that impact pharmacology in women. Consider for example, what an individual might need to know about medications. Perhaps you are counseling someone who is indicating they are having significant side effects or the medication isn’t as effective as they expected. Your knowledge of pharmacology in women would assist you in guiding the individual in the community setting.
Major points include the differences in women are based on differences in:
Absorption
Distribution
Metabolism
Elimination
Other effects include those related to fluctuations in estrogen and progesterone that change with menstrual cycles, pregnancy, menopause, and the effects of hormonal birth control. Sections to read include:
Pharmacokinetics and Pharmacodynamics
absorption
distribution
metabolism
elimination
influence of the gut microbiome
influence of sex-specific factors

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